Intended Use:
ARA-290 is intended for research purposes only. It is widely studied in models involving neuropathy, inflammation, and tissue repair.
Storage:
Store in a cool, dry environment away from direct sunlight. After reconstitution, refrigerate at 2–8°C.
Solubility:
Reconstitute with bacteriostatic water (BAC water) for optimal performance.
Vial Size:
Standard 3ml vial (can accommodate up to 3ml BAC water).
Shelf Life:
Handling:
Use sterile techniques during preparation and handling.
Neuropathic Pain Studies
Preclinical and clinical research suggests ARA-290 may significantly reduce neuropathic pain by targeting inflammation in nerve tissues without affecting normal nerve function.
Anti-Inflammatory Effects
ARA-290 has shown the ability to reduce pro-inflammatory cytokines, helping regulate excessive immune responses in various experimental models.
Tissue Repair & Regeneration
Studies indicate that ARA-290 may support tissue healing and cellular repair, especially in damaged nerve and vascular systems.
Metabolic & Microvascular Function
Emerging research shows improvements in microcirculation and metabolic signaling, making it relevant for studies involving small fiber neuropathy and vascular dysfunction.
ARA-290 works by selectively binding to the innate repair receptor (IRR), a receptor complex involved in tissue protection and healing.
Once activated, it:
Unlike traditional EPO, ARA-290 does not activate receptors responsible for red blood cell production, which allows it to focus purely on repair and anti-inflammatory pathways.
ARA-290 is a synthetic peptide derived from erythropoietin (EPO), designed to retain tissue-protective and anti-inflammatory properties without stimulating red blood cell production. It is widely studied in models involving nerve repair, inflammation, and metabolic dysfunction.
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